Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.70 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511247 | 0.88 | LNPEP (0.76) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL7511243 | 0.88 | LNPEP (0.76) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL2972303 | 0.88 | LNPEP (0.68) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL13330073 | 0.88 | LNPEP (0.68) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL13669575 | 0.88 | LNPEP (0.68) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL13885677 | 0.88 | GAA (0.73) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL3928164 | 0.88 | LNPEP (0.67) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL3928165 | 0.88 | LNPEP (0.67) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL8721006 | 0.85 | LNPEP (0.68) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL11359792 | 0.85 | LNPEP (0.71) | LNPEPERAP2ERAP1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008665-B | Compound with tumor proliferation inhibition function and preparation method and application thereof | 北京大学 | 2021-03-16 | — | — | CN | disclosed |