Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.68 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919649 | 0.88 | LNPEP (0.70) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL7511243 | 0.87 | LNPEP (0.76) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL13330073 | 0.87 | LNPEP (0.68) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL7511247 | 0.87 | LNPEP (0.76) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL13669575 | 0.87 | LNPEP (0.68) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL3928164 | 0.86 | LNPEP (0.67) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL3928165 | 0.86 | LNPEP (0.67) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL13885677 | 0.86 | GAA (0.73) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL11359792 | 0.84 | LNPEP (0.71) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL6030105 | 0.83 | GAA (0.68) | LNPEPERAP2ERAP1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| US-7777038-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-08-17 | — | — | US | disclosed |
| US-20070179173-A1 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179173-A1 | Carbostyril compound | GTF2F1, F3, GTF2F2 | LNPEP 4528/4885ERAP2 4663/4885ERAP1 4681/4885 |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | GTF2F1, F3, GTF2F2 | LNPEP 4528/4885ERAP2 4663/4885ERAP1 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.