SCHEMBL2891981

SCHEMBL2891981

[NH]C(=O)c1c2ccccc2cc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
KDM4E B2RXH2 3/20 0.65
HPGD P15428 3/20 0.65
HSD17B10 Q99714 2/20 0.65
CYP1A2 P05177 1/20 0.65
GLA P06280 1/20 0.65
CYP2C19 P33261 1/20 0.65
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
GAA P10253 1/20 0.42
CYP3A4 P08684 1/20 0.42
POLB P06746 1/20 0.42
GPR35 Q9HC97 1/20 0.42
ME2 P23368 1/20 0.41
ME1 P48163 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10351077 0.82 CYP1A2 (0.50) ALDH1A1MEN1KMT2AKDM4EHPGD
Anthracene-9-Carboxylic Acid SCHEMBL29352186 0.79 MEN1 (1.00) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL4899613 0.79 ALDH1A1 (0.68) ALDH1A1MEN1KMT2AKDM4EHPGD
Anthracene-9-Carboxylic Acid SCHEMBL122832 0.79 MEN1 (1.00) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL23079083 0.77 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL20669622 0.77 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL29491183 0.77 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL67303 0.77 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AKDM4EHPGD
Anthracene-9-Carboxylic Acid SCHEMBL7054301 0.77 MEN1 (0.95) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL28748280 0.77 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-12-23 US disclosed
EP-3858909-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-08-04 EP disclosed
CN-112839988-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2021-05-25 CN disclosed
WO-2020067144-A1 NUCLEATING AGNET, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF 株式会社ADEKA 2020-04-02 WO disclosed
EP-1718629-B1 Benzopyran compounds useful for the treatment of arrhytmia NISSAN CHEMICAL IND LTD (JP) 2012-12-26 EP disclosed
US-7781483-B2 Benzopyran compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-08-24 US disclosed
US-20070299130-A1 Benzopyran Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-12-27 US disclosed
EP-1718629-A2 BENZOPYRAN COMPOUNDS USEFUL FOR THE TREATMENT OF ARRHYTMIA Nissan Chemical Industries, Ltd. (JP) 2006-11-08 EP disclosed
EP-1020446-B1 NAPHTHALIMIDOBENZAMIDE DERIVATIVES TAIHO PHARMACEUTICAL CO LTD (JP) 2006-03-15 EP disclosed
WO-2005080368-A2 BENZOPYRAN COMPOUND USEFUL FOR THE TREATMENT OF ARRHYTMIA NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-01 WO disclosed
US-6300331-B1 DRUGS AS ANTITUMOR AGENTS OR ANTICARCINOGENIC AGENTS TAIHO PHARMACEUTICAL CO., LTD. (JP) 2001-10-09 US disclosed
EP-1020446-A1 NAPHTHALIMIDOBENZAMIDE DERIVATIVES TAIHO PHARMACEUTICAL CO., LTD. (JP) 2000-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF NOC2L, RIF1, NAP1L1 ALDH1A1 2699/4885MEN1 1254/4885KMT2A 1121/4885
US-20070299130-A1 Benzopyran Compound NR0B1, CYP2B6, RYR2 ALDH1A1 2971/4885MEN1 3048/4885KMT2A 2949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.