SCHEMBL67303

SCHEMBL67303

CC(=O)c1c2ccccc2cc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
HSD17B10 Q99714 3/20 0.65
KDM4E B2RXH2 3/20 0.65
HPGD P15428 2/20 0.65
CYP1A2 P05177 1/20 0.65
GLA P06280 1/20 0.65
CYP2C19 P33261 1/20 0.65
MAPT P10636 2/20 0.55
NCEH1 Q6PIU2 1/20 0.49
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
TP53 P04637 1/20 0.46
THRB P10828 1/20 0.43
GAA P10253 2/20 0.42
NSD2 O96028 1/20 0.42
POLB P06746 1/20 0.42
MCL1 Q07820 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29491183 1.00 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AHSD17B10KDM4E
SCHEMBL1669213 0.84 KDM4E (0.52) ALDH1A1MEN1KMT2AHSD17B10KDM4E
SCHEMBL31146421 0.83 THRB (0.52) ALDH1A1MEN1KMT2AHSD17B10KDM4E
SCHEMBL181822 0.83 THRB (0.52) ALDH1A1MEN1KMT2AHSD17B10KDM4E
SCHEMBL2944393 0.82 MEN1 (0.50) ALDH1A1MEN1KMT2AHSD17B10KDM4E
SCHEMBL9719299 0.82 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AHSD17B10KDM4E
Anthracene-9-Carboxylic Acid SCHEMBL28243282 0.80 MEN1 (0.91) ALDH1A1MEN1KMT2AHSD17B10KDM4E
SCHEMBL3557162 0.79 ALDH1A1 (0.57) ALDH1A1MEN1KMT2AHSD17B10KDM4E
SCHEMBL28655048 0.79 ALDH1A1 (0.61) ALDH1A1MEN1KMT2AHSD17B10KDM4E
Anthracene-9-Carboxylic Acid SCHEMBL122832 0.79 MEN1 (1.00) ALDH1A1MEN1KMT2AHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 802 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684187-A Preparation method of vitamin D3 湖南新合新生物医药有限公司 2025-03-25 CN claimed
CN-119661577-A Preparation method of maxacalcitol intermediate B 杭州福斯特药业有限公司 2025-03-21 CN claimed
CN-119504538-A Preparation method of maxacalcitol impurity C 南京海融医药科技股份有限公司 2025-02-25 CN claimed
CN-119285515-A Preparation method of fluoro-calcitol 南京海融医药科技股份有限公司 2025-01-10 CN claimed
CN-118791414-A Preparation method and application of calcipotriol related isomer impurities 南京海融医药科技股份有限公司 2024-10-18 CN claimed
CN-114685235-B Method and device for separating 1-decene from Fischer-Tropsch synthesis stable heavy oil 国家能源集团宁夏煤业有限责任公司 2024-08-23 CN claimed
CN-115160199-B Method for preparing calcitriol, intermediate compound thereof and preparation method of intermediate compound 江西淳迪生物科技有限公司 2024-06-04 CN claimed
CN-114644543-B Method and device for separating and purifying 1-dodecene from Fischer-Tropsch synthesis stable heavy oil 国家能源集团宁夏煤业有限责任公司 2024-01-16 CN claimed
CN-116789581-A Impurity of related isomer of idecalcitol, preparation method and application 南京海融医药科技股份有限公司 2023-09-22 CN claimed
CN-116102479-A Preparation method and application of calcipotriol related isomer impurities 南京海融医药科技股份有限公司 2023-05-12 CN claimed
EP-2167481-A1 METHOD FOR PRODUCING PROPYLENE OXIDE Sumitomo Chemical Company, Limited (JP) 2010-03-31 EP claimed
CN-101679332-A Method for producing propylene oxide SUMITOMO CHEMICAL CO 2010-03-24 CN claimed
CN-101400649-A Isomerization of pharmaceutical intermediates LEO PHARMA AS (DK) 2009-04-01 CN claimed
WO-2008156205-A1 METHOD FOR PRODUCING PROPYLENE OXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-12-24 WO claimed
EP-1844010-A1 ISOMERISATION OF PHARMACEUTICAL INTERMEDIATES LEO PHARMA A/S (DK) 2007-10-17 EP claimed
US-20070215455-A1 Isomerisation of pharmaceutical intermediates LEO PHARMA A/S (DK) 2007-09-20 US claimed
WO-2007082533-A1 ISOMERISATION OF PHARMACEUTICAL INTERMEDIATES LEO PHARMA A/S (DK) 2007-07-26 WO claimed
US-4598022-A PRINTED CIRCUITS OLIN CORPORATION (US) 1986-07-01 US claimed
US-4526806-A Forming plasma of polar organic species and of nitrogen and hydrogen, exposing copper substrate to plasma OLIN CORPORATION (US) 1985-07-02 US claimed
US-4264695-A LAMINATED ELECTROCONDUCTIVE SUPPORTS RICOH CO., LTD. (JP) 1981-04-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070215455-A1 Isomerisation of pharmaceutical intermediates CYP24A1, CYP2R1, VDR ALDH1A1 532/4885MEN1 1145/4885KMT2A 4020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.