Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084929 | 1.00 | MAPT (0.41) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL10119242 | 0.78 | MAPT (0.56) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL28981145 | 0.77 | GAA (0.58) | MAPTGAAALDH1A1CYP3A4 | |
| SCHEMBL28920148 | 0.71 | MAPT (0.37) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL114307 | 0.70 | KDM4E (0.52) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL1361840 | 0.70 | KDM4E (0.52) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL16581288 | 0.69 | CRHBP (0.46) | GAAKDM4EALDH1A1LMNAHTT | |
| SCHEMBL14675666 | 0.69 | KDM4E (0.31) | GAAKDM4EALDH1A1HPGD | |
| SCHEMBL5074465 | 0.69 | KDM4E (0.45) | MAPTGAAKDM4EALDH1A1USP2 | |
| Bromide SCHEMBL7921765 | 0.68 | KDM4E (0.50) | MAPTGAAKDM4EALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490709-A | KRASG12D inhibitor and application thereof in medicine | 四川海思科制药有限公司 | 2022-12-20 | — | — | CN | disclosed |