Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23174552 | 0.77 | GAA (0.39) | MAPTGAA | |
| SCHEMBL10119242 | 0.74 | MAPT (0.56) | MAPTGAAADRB2KDM4EALDH1A1 | |
| SCHEMBL31243002 | 0.73 | CYP3A4 (0.39) | MAPTGAAALDH1A1HTT | |
| SCHEMBL28906398 | 0.73 | CYP3A4 (0.39) | MAPTGAAALDH1A1HTT | |
| SCHEMBL28920164 | 0.71 | MAPT (0.41) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL30084929 | 0.71 | MAPT (0.41) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL15769819 | 0.68 | KDM4E (0.46) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL14744326 | 0.67 | KHK (0.39) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL30319931 | 0.67 | KDM4E (0.40) | MAPTGAAADRB2KDM4EALDH1A1 | |
| SCHEMBL20680925 | 0.66 | ADRB2 (0.31) | ADRB2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490709-A | KRASG12D inhibitor and application thereof in medicine | 四川海思科制药有限公司 | 2022-12-20 | — | — | CN | disclosed |