Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28920504 | 0.88 | MAPT (0.43) | TP53POLBRXFP1MAPTLMNA | |
| SCHEMBL28920485 | 0.86 | GPR119 (0.51) | POLBRXFP1MAPTSTS | |
| SCHEMBL30091314 | 0.85 | TP53 (0.48) | TP53POLBRXFP1MAPTLMNA | |
| SCHEMBL28920455 | 0.82 | HTR6 (0.49) | LMNASTS | |
| SCHEMBL28920511 | 0.82 | MAPT (0.46) | TP53POLBMAPTLMNAALDH1A1 | |
| SCHEMBL30091230 | 0.82 | HTR6 (0.57) | TP53POLBRXFP1LMNANPSR1 | |
| SCHEMBL28920390 | 0.82 | HTR6 (0.57) | TP53POLBRXFP1LMNANPSR1 | |
| SCHEMBL28920508 | 0.79 | HTR6 (0.49) | — | |
| SCHEMBL28920497 | 0.79 | CPT2 (0.47) | TP53MAPTSTS | |
| SCHEMBL28920364 | 0.79 | HTR6 (0.47) | STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232362-B | Aromatic heterocyclic derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |