Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28920459 | 0.94 | CCNT1 (0.45) | CCNT1CDK9HTR6GPR119 | |
| SCHEMBL28920387 | 0.90 | STS (0.45) | HTR6 | |
| SCHEMBL28920384 | 0.90 | HTR6 (0.43) | HTR6HTR1AHTR7 | |
| SCHEMBL28920367 | 0.89 | HTR6 (0.45) | HTR6LMNAHTTSMN1; SMN2HTR1A | |
| SCHEMBL30091235 | 0.86 | HTR6 (0.47) | HTR6LMNAHTTSMN1; SMN2HTR1A | |
| SCHEMBL28920419 | 0.86 | HTR6 (0.55) | HTR6LMNAHTTSMN1; SMN2HTR1A | |
| SCHEMBL30091105 | 0.86 | HTR6 (0.55) | HTR6LMNAHTTSMN1; SMN2HTR1A | |
| SCHEMBL28920406 | 0.85 | GPR119 (0.51) | GPR119 | |
| SCHEMBL30091099 | 0.84 | HTR6 (0.59) | HTR6 | |
| SCHEMBL28920395 | 0.84 | HTR6 (0.59) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232362-B | Aromatic heterocyclic derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |