SCHEMBL28922673

SCHEMBL28922673

CC(O)(Br)C(O)C1CCCCCCCCCCCCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
KDM4E B2RXH2 2/20 0.35
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SHBG P04278 1/20 0.34
GABBR2 O75899 1/20 0.34
GABBR1 Q9UBS5 1/20 0.34
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
PDK4 Q16654 1/20 0.32
EPHX1 P07099 2/20 0.32
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
DHODH Q02127 1/20 0.32
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9221102 0.81 TP53 (0.39) TP53KDM4EGMNNLMNAMAPT
SCHEMBL8976097 0.78 TP53 (0.41) TP53KDM4EGMNNLMNAMAPT
SCHEMBL14443275 0.78 TP53 (0.41) TP53KDM4EGMNNLMNAMAPT
SCHEMBL14443274 0.78 TP53 (0.41) TP53KDM4EGMNNLMNAMAPT
SCHEMBL16230660 0.75 TP53 (0.37) TP53KDM4EGMNNLMNAMAPT
SCHEMBL16230728 0.75 TP53 (0.37) TP53KDM4EGMNNLMNAMAPT
SCHEMBL10104528 0.75 TP53 (0.37) TP53KDM4EGMNNLMNAMAPT
SCHEMBL28505213 0.71 TP53 (0.40) TP53KDM4EGMNNLMNAMAPT
SCHEMBL16805015 0.70 UGT2B7 (0.33) TP53KDM4EGMNNLMNAMAPT
SCHEMBL6370679 0.70 PDK1 (0.37) TP53KDM4EGMNNLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372207-B Synthesis method of muscone intermediate 2-cyclopentadecanone 无锡济煜山禾药业股份有限公司 2022-05-06 CN claimed
CN-113372207-A Synthesis method of muscone intermediate 2-cyclopentadecanone 无锡济煜山禾药业股份有限公司 2021-09-10 CN claimed