Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14443274 | 0.82 | TP53 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL14443275 | 0.82 | TP53 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL8976097 | 0.82 | TP53 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL28922673 | 0.81 | TP53 (0.37) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL16230728 | 0.79 | TP53 (0.37) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL16230660 | 0.79 | TP53 (0.37) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL10104528 | 0.79 | TP53 (0.37) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL11101108 | 0.75 | SHBG (0.37) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL28505213 | 0.75 | TP53 (0.40) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL16805015 | 0.74 | UGT2B7 (0.33) | TP53KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426194-A | Isolation and structure of Halistatin 1 | ARIZONA BOARD OF REGENTS, A BODY CORPORATE ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1995-06-20 | — | — | US | disclosed |
| US-5352804-A | Anticancer drugs | ARIZONA BOARD OF REGENTS, A BODY CORPORATE, ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1994-10-04 | — | — | US | disclosed |
| EP-0608110-A1 | Isolation and structure of halistatin 2, and its use as an anti-tumor agent | ARIZONA BOARD OF REGENTS (US) | 1994-07-27 | — | — | EP | disclosed |
| EP-0608108-A1 | Isolation and structure of halistatin 1, and its use as an anti-tumor agent | ARIZONA BOARD OF REGENTS (US) | 1994-07-27 | — | — | EP | disclosed |