SCHEMBL28922902

SCHEMBL28922902

C=CCOc1ccc(Oc2cc[c]cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.47
CA1 P00915 5/20 0.47
CA9 Q16790 5/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2D6 P10635 1/20 0.40
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
ALDH1A1 P00352 3/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482465 0.92 CA12 (0.48) CA12CA1CA9CA2CA7
SCHEMBL3487338 0.88 CA12 (0.57) CA12CA1CA9CA2CA7
SCHEMBL19856490 0.85 CA12 (0.47) CA12CA1CA9CA2CA7
1,4-Diallyloxybenzene SCHEMBL302448 0.81 CA12 (0.63) CA12CA1CA9CA2CA7
SCHEMBL5973615 0.80 LTA4H (0.55) CA12CA1CA9CA2CA7
SCHEMBL5208927 0.78 CA12 (0.49) CA12CA1CA9CA2CA7
SCHEMBL5773100 0.78 ALDH1A1 (0.56) CA12CA1CA9CA2CA7
SCHEMBL3548978 0.78 HPGD (0.49) CA12CA1CA9CA2CA7
SCHEMBL3416077 0.78 LTA4H (0.57) CA12CA1CA9CA2CA7
SCHEMBL5973047 0.78 CA12 (0.49) CA12CA1CA9CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115397891-B Polysiloxanes with radiation-crosslinkable and moisture-crosslinkable groups 瓦克化学股份公司 2024-02-02 CN disclosed
CN-115397891-A Polysiloxanes with radiation-crosslinkable and moisture-crosslinkable groups 瓦克化学股份公司 2022-11-25 CN disclosed