Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027208 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAALDH1A1HPGDRECQL | |
| SCHEMBL14027543 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNAHPGDRECQL | |
| SCHEMBL28631726 | 0.77 | RECQL (0.72) | SMN1; SMN2LMNAALDH1A1RECQLRAB9A | |
| SCHEMBL5484113 | 0.73 | SMN1; SMN2 (0.82) | SMN1; SMN2LMNAHSD17B10ALDH1A1RECQL | |
| SCHEMBL14027202 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAALDH1A1HPGDRECQL | |
| SCHEMBL5368754 | 0.71 | ALOX15 (0.56) | SMN1; SMN2LMNAALOX15CRHBPCRHR2 | |
| SCHEMBL14027548 | 0.71 | RECQL (0.72) | SMN1; SMN2LMNARECQLRAB9ANPC1 | |
| SCHEMBL14027549 | 0.69 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1HPGDRECQL | |
| SCHEMBL5321349 | 0.69 | ALOX15 (0.53) | SMN1; SMN2LMNAALOX15CRHBPCRHR2 | |
| SCHEMBL6207563 | 0.67 | RECQL (0.71) | SMN1; SMN2LMNAALOX15HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615792-B | 2-benzylthio-5-methyl-4, 7-dihydro- [1,2,4] triazolo [1,5-a ] pyrimidine derivatives | HEBEI UNIVERSITY OF TECHNOLOGY (CN) | 2021-08-31 | — | — | CN | claimed |
| CN-110615792-A | 2-benzylthio-5-methyl-4, 7-dihydro- [1,2,4] triazolo [1,5-a ] pyrimidine derivatives | 河北工业大学 | 2019-12-27 | — | — | CN | claimed |
| CN-110615792-B | 2-benzylthio-5-methyl-4, 7-dihydro- [1,2,4] triazolo [1,5-a ] pyrimidine derivatives | HEBEI UNIVERSITY OF TECHNOLOGY (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-110615792-A | 2-benzylthio-5-methyl-4, 7-dihydro- [1,2,4] triazolo [1,5-a ] pyrimidine derivatives | 河北工业大学 | 2019-12-27 | — | — | CN | disclosed |