Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | DGKA | P23743 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 4/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174985 | 0.90 | LMNA (0.73) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28554498 | 0.90 | LMNA (0.63) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28942531 | 0.90 | LMNA (0.63) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL8540115 | 0.89 | LMNA (0.61) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL29208949 | 0.88 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28660228 | 0.88 | LMNA (0.68) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28663700 | 0.88 | LMNA (0.68) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL3239678 | 0.86 | LMNA (0.79) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL7816036 | 0.86 | LMNA (0.79) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL7203853 | 0.85 | KDM4E (0.57) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115212173-A | Ambroxol hydrochloride spherical sustained-release particles, preparation method and application | 上海现代药物制剂工程研究中心有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-115212173-A | Ambroxol hydrochloride spherical sustained-release particles, preparation method and application | 上海现代药物制剂工程研究中心有限公司 | 2022-10-21 | — | — | CN | disclosed |