SCHEMBL3239678

SCHEMBL3239678

CCCCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OCC(O)CO

nearest known ligand 0.79

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.79
KDM4E B2RXH2 1/20 0.79
DUSP3 P51452 1/20 0.79
MEN1 O00255 1/20 0.79
KMT2A Q03164 1/20 0.79
DGKA P23743 1/20 0.68
PRKCA P17252 4/20 0.66
PRKCE Q02156 2/20 0.66
PRKCQ Q04759 2/20 0.66
PRKCD Q05655 2/20 0.66
ALDH1A1 P00352 1/20 0.62
MAPT P10636 1/20 0.59
FAAH O00519 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7816036 1.00 LMNA (0.79) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL2302665 0.95 LMNA (0.77) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL2701555 0.95 LMNA (0.77) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL5416233 0.95 LMNA (0.77) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL5425135 0.92 LMNA (0.68) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL5420360 0.92 LMNA (0.68) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL5418433 0.92 LMNA (0.68) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL8781081 0.92 DGKA (0.82) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL9075201 0.92 LMNA (0.68) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL14151288 0.92 DGKA (0.82) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7744909-B2 Dispersions for the formulation of slightly or poorly soluble agents ABBOTT GMBH & CO., KG (DE) 2010-06-29 US claimed
EP-1305006-B1 PROCESS FOR THE MANUFACTURE OF DISPERSIONS FOR FORMULATING SLIGHTLY OR POORLY SOLUBLE ACTIVE INGREDIENTS ABBOTT GMBH & CO KG (DE) 2008-07-16 EP claimed
US-20060188534-A1 Dispersions for the formulation of slightly or poorly soluble agents ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2006-08-24 US claimed
US-7060285-B2 Dispersions for the formulation of slightly or poorly soluble agents PHARMASOL GMBH (DE) 2006-06-13 US claimed
US-20030059470-A1 Dispersions for the formulation of slightly or poorly soluble agents ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2003-03-27 US claimed