Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14881136 | 0.80 | PNMT (0.47) | GAAMAPT | |
| SCHEMBL28923868 | 0.80 | ALDH1A1 (0.43) | GAAMAPT | |
| SCHEMBL12049299 | 0.80 | MEN1 (0.51) | GRIN2BSIGMAR1GAAMAPT | |
| SCHEMBL19987645 | 0.79 | ALDH1A1 (0.48) | GAAMAPT | |
| SCHEMBL4989773 | 0.78 | MEN1 (0.47) | — | |
| SCHEMBL23010557 | 0.77 | ALDH1A1 (0.47) | GAAMAPTHTR2A | |
| SCHEMBL3125014 | 0.77 | PNMT (0.56) | GRIN2BSIGMAR1 | |
| SCHEMBL28923894 | 0.77 | ALDH1A1 (0.47) | GAAMAPTHTR2A | |
| Naphthalene SCHEMBL7011468 | 0.76 | ALDH1A1 (0.40) | GAAMAPT | |
| SCHEMBL7381467 | 0.76 | HTR2A (0.46) | GAAMAPTHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437123-B | Method for synthesizing optically pure 2-substituted indoline compound through dynamic kinetic resolution | 华中师范大学 | 2023-01-03 | — | — | CN | disclosed |