Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22620771 | 0.84 | MAPT (0.33) | PKMNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20535994 | 0.83 | GRIK1 (0.34) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29063150 | 0.83 | CA1 (0.37) | NPC1MAPTRAB9ASMN1; SMN2CAPN1 | |
| SCHEMBL20535997 | 0.83 | GRIK1 (0.34) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23148058 | 0.83 | SLC9A3 (0.36) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23148082 | 0.83 | PDE2A (0.36) | MAPTSMN1; SMN2 | |
| SCHEMBL29062947 | 0.82 | NPC1 (0.35) | NPC1MAPTRAB9ASMN1; SMN2CAPN1 | |
| SCHEMBL22620737 | 0.81 | MAPT (0.41) | PKMMAPTRAB9A | |
| SCHEMBL28457793 | 0.81 | MAPT (0.41) | PKMMAPTRAB9A | |
| SCHEMBL23148042 | 0.77 | ALDH1A1 (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |