SCHEMBL28926480

SCHEMBL28926480

Cc1ccc2oc(C3CCCO3)cc(=O)c2c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
HTT P42858 1/20 0.46
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 3/20 0.45
TP53 P04637 2/20 0.45
CYP3A4 P08684 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CSNK2A2 P19784 1/20 0.43
CSNK2B P67870 1/20 0.43
CSNK2A1 P68400 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KCNA5 P22460 1/20 0.41
KCNH2 Q12809 1/20 0.41
STS P08842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28926476 1.00 MAPT (0.46) MAPTHTTKDM4EALDH1A1TP53
SCHEMBL29973080 1.00 MAPT (0.46) MAPTHTTKDM4EALDH1A1TP53
SCHEMBL29973110 0.84 GABRP (0.45) MAPTTP53CYP3A4MAPK1RAB9A
SCHEMBL28926371 0.84 GABRP (0.45) MAPTTP53CYP3A4MAPK1RAB9A
SCHEMBL28926392 0.84 ADCY1 (0.47) MAPTKDM4EALDH1A1TP53HPGD
SCHEMBL29973037 0.84 ADCY1 (0.47) MAPTKDM4EALDH1A1TP53HPGD
SCHEMBL28926369 0.84 GABRP (0.45) MAPTTP53CYP3A4MAPK1RAB9A
SCHEMBL28926472 0.84 GABRP (0.47) KDM4EALDH1A1NPC1RAB9ASTS
SCHEMBL28926474 0.84 GABRP (0.47) KDM4EALDH1A1NPC1RAB9ASTS
SCHEMBL29972860 0.84 GABRP (0.47) KDM4EALDH1A1NPC1RAB9ASTS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115385876-B Method for constructing C-C bond by photocatalysis activation of alpha-position C-H bond of tetrahydrofuran 中国科学院理化技术研究所 2024-01-30 CN disclosed
CN-115385876-A Method for constructing C-C bond by photocatalytic activation of alpha-position C-H bond of tetrahydrofuran 中国科学院理化技术研究所 2022-11-25 CN disclosed