Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 12/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591043 | 0.84 | PKM (0.69) | PKMALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2592155 | 0.75 | PKM (0.73) | PKMALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2591579 | 0.74 | PKM (1.00) | PKMALDH1A1PKLR | |
| SCHEMBL30114544 | 0.74 | PKM (1.00) | PKMALDH1A1PKLR | |
| SCHEMBL12633834 | 0.73 | PKM (0.79) | PKMALDH1A1LMNASMN1; SMN2PKLR | |
| SCHEMBL4608466 | 0.73 | PKM (0.57) | PKMALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14089190 | 0.72 | PKM (0.60) | PKMALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3248876 | 0.72 | ALDH1A1 (0.62) | PKMALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13577040 | 0.71 | PSEN1 (0.50) | LMNAL3MBTL1 | |
| SCHEMBL4712443 | 0.70 | PKM (0.57) | PKMALDH1A1HTTL3MBTL1PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572259-A | Arylsulfonamide compounds and uses thereof | 四川科伦博泰生物医药股份有限公司 | 2023-01-06 | — | — | CN | disclosed |