Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696827 | 0.76 | CCNC (0.35) | POLBLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28552197 | 0.76 | RAB9A (0.48) | MEN1POLBKMT2ALMNAMAPT | |
| SCHEMBL4135468 | 0.75 | ATM (0.46) | CYP3A4PDE4DHDAC3HDAC4HDAC1 | |
| SCHEMBL28106099 | 0.72 | HCAR2 (0.56) | — | |
| SCHEMBL1703067 | 0.72 | ICAM1 (0.47) | CYP3A4ICAM1SELEVCAM1HDAC3 | |
| Nitrous Acid SCHEMBL28928125 | 0.71 | HCAR2 (0.41) | CYP3A4ICAM1SELEVCAM1HDAC3 | |
| Hydrochloric Acid SCHEMBL5010437 | 0.70 | ICAM1 (0.46) | CYP3A4ICAM1SELEVCAM1HDAC3 | |
| SCHEMBL111872 | 0.69 | HCAR2 (0.46) | CYP3A4ICAM1SELEVCAM1HDAC3 | |
| SCHEMBL1666884 | 0.69 | ALDH1A1 (0.54) | CYP3A4ICAM1SELEVCAM1HDAC3 | |
| SCHEMBL28558485 | 0.68 | KMT2A (0.35) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490668-A | Compounds and compositions for treating diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2021-10-08 | — | — | CN | disclosed |