SCHEMBL28928372

SCHEMBL28928372

[c]1ccc(-c2ccc3ccc4ccc(-c5ccccc5)nc4c3n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
RAB9A P51151 3/20 0.46
ASIC3 Q9UHC3 1/20 0.39
MKNK2 Q9HBH9 1/20 0.38
ADORA2A P29274 2/20 0.37
AURKA O14965 1/20 0.37
HSP90AA1 P07900 1/20 0.37
PRKACA P17612 1/20 0.37
ALDH1A1 P00352 3/20 0.37
ADORA1 P30542 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP3A4 P08684 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
NPC1 O15118 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29441293 0.87 MEN1 (0.59) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL1753930 0.87 MEN1 (0.59) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL17899333 0.85 MEN1 (0.56) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL30870479 0.85 MEN1 (0.56) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL30870477 0.85 MEN1 (0.56) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL10032304 0.85 MEN1 (0.56) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL28653700 0.83 PARP1 (0.44) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL20250404 0.83 MEN1 (0.54) PARP1MEN1KMT2ARAB9AASIC3
Hydrochloric Acid SCHEMBL4387023 0.83 RAB9A (0.54) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL30595380 0.83 MEN1 (0.54) PARP1MEN1KMT2ARAB9AASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710662-A Heterocyclic compound and organic light-emitting device including same LT素材株式会社 2021-11-26 CN disclosed