Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30242496 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL27156530 | 0.84 | MEN1 (0.50) | MEN1KMT2AALDH1A1GRM5HTR2A | |
| SCHEMBL29771862 | 0.83 | KMT2A (0.49) | MEN1KMT2AMAPTALDH1A1GRM5 | |
| SCHEMBL2205991 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30242551 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25947319 | 0.80 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP2D6GRM5 | |
| SCHEMBL29771861 | 0.79 | MEN1 (0.52) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL12559535 | 0.77 | MEN1 (0.55) | MEN1KMT2AGRM5DRD2AOC3 | |
| SCHEMBL7894568 | 0.75 | ATM (0.42) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5986824 | 0.74 | MEN1 (0.55) | MEN1KMT2AGRM5DRD2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120090-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-115916759-A | Substituted quinazoline compound, preparation method, pharmaceutical composition and application thereof | 南京红云生物科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115697996-A | Alkenyl pyrimidine compound, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113717156-A | EGFR inhibitor, preparation method and application thereof | 南京红云生物科技有限公司 | 2021-11-30 | — | — | CN | disclosed |