Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 4/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627143 | 0.85 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL28646116 | 0.84 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL28499242 | 0.83 | ALDH1A1 (0.51) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL28930104 | 0.81 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL29035863 | 0.78 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL28670338 | 0.73 | HSP90AA1 (0.31) | — | |
| SCHEMBL30760997 | 0.73 | CYP1A2 (0.43) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL24569796 | 0.69 | CNR1 (0.57) | ADORA3ADORA2AADORA1CNR1CNR2 | |
| SCHEMBL28632315 | 0.66 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL4866386 | 0.61 | NPC1 (0.46) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486883-A | Purinyl fluorescent probe EDPH and application thereof in detection of content of hydrogen sulfide or Hela cell imaging | 江苏科技大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-114014891-B | Purine ring modified fluorescent probe and application thereof in detection of cobalt ions | 江苏科技大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-114106018-B | Metal ion detection fluorescent probe based on purine parent, and preparation method and application thereof | 江苏科技大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113980021-B | Preparation method and application of fluorescent probe for detecting bimetallic ions | 江苏科技大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-114409646-B | Fluorescent probe for detecting copper ions and preparation method and application thereof | 江苏科技大学 | 2022-12-02 | — | — | CN | disclosed |
| CN-114409646-A | Fluorescent probe for detecting copper ions and preparation method and application thereof | 江苏科技大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-114106018-A | Purine matrix-based metal ion detection fluorescent probe and preparation method and application thereof | 江苏科技大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-114014891-A | Purine ring modified fluorescent probe and application thereof in cobalt ion detection | 江苏科技大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-113980021-A | Preparation method and application of fluorescent probe for detecting bimetallic ions | 江苏科技大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113735858-A | Purine matrix-based aluminum ion detection fluorescent probe and preparation method and application thereof | 坛墨质检科技股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113512041-A | Purine matrix-based zinc ion detection fluorescent probe and preparation method and application thereof | 坛墨质检科技股份有限公司 | 2021-10-19 | — | — | CN | disclosed |