Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.32 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762881 | 0.86 | CSNK1D (0.41) | GRM2POLBPIK3CDPIK3R2PIK3CA | |
| SCHEMBL1762849 | 0.85 | HSD17B10 (0.44) | GRM2POLBHSD11B1MAPTCSNK1D | |
| SCHEMBL1762911 | 0.83 | POLB (0.36) | GRM2POLBPDE10ACSNK1DCSNK1E | |
| SCHEMBL27708025 | 0.83 | SCN9A (0.40) | POLBHSD11B1CSNK1DCSNK1E | |
| SCHEMBL28930107 | 0.83 | POLB (0.41) | GRM2POLBPIK3CDPIK3R2PIK3CA | |
| SCHEMBL3232405 | 0.82 | CSNK1D (0.41) | POLBCSNK1DCSNK1EHSD17B10PTGER4 | |
| SCHEMBL27719734 | 0.82 | SOS1 (0.35) | GRM2POLBHSD17B10 | |
| SCHEMBL18691186 | 0.82 | POLB (0.35) | GRM2POLBCSNK1DCSNK1EHSD17B10 | |
| SCHEMBL1763226 | 0.81 | CSNK1E (0.41) | POLBPDE10AMAPTCSNK1DCSNK1E | |
| SCHEMBL3329484 | 0.81 | CSNK1D (0.41) | GRM2POLBCSNK1DCSNK1EMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113788790-A | Aromatic heterocyclic amide derivative and application thereof | 华东理工大学 | 2021-12-14 | — | — | CN | disclosed |