SCHEMBL1763226

SCHEMBL1763226

Cn1nc(C(F)F)c(C(N)=O)c1-c1ccccc1-c1cc(F)ccc1F

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 5/20 0.41
CSNK1D P48730 4/20 0.41
DHODH Q02127 2/20 0.41
MAPT P10636 2/20 0.38
TP53 P04637 1/20 0.38
SCN9A Q15858 3/20 0.36
KIF11 P52732 3/20 0.35
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTPN1 P18031 1/20 0.34
SLC9A1 P19634 1/20 0.34
PDE10A Q9Y233 1/20 0.33
DHFR P00374 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3329484 0.91 CSNK1D (0.41) CSNK1ECSNK1DDHODHPOLB
SCHEMBL1762881 0.90 CSNK1D (0.41) CSNK1ECSNK1DDHODHMAPTTP53
SCHEMBL1762911 0.89 POLB (0.36) CSNK1ECSNK1DDHODHSCN9APOLB
SCHEMBL29198567 0.86 DHODH (0.39) CSNK1ECSNK1DDHODH
SCHEMBL18691186 0.85 POLB (0.35) CSNK1ECSNK1DDHODHSCN9APOLB
SCHEMBL19436813 0.85 CSNK1E (0.38) CSNK1ECSNK1DDHODH
SCHEMBL30132994 0.85 CSNK1E (0.38) CSNK1ECSNK1DDHODH
SCHEMBL1763152 0.84 CSNK1E (0.43) CSNK1ECSNK1DPOLB
SCHEMBL28483197 0.84 DHODH (0.36) CSNK1ECSNK1DDHODH
SCHEMBL1762883 0.84 POLB (0.38) CSNK1ECSNK1DDHODHPOLBPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263327-B2 Enzymatic method for the production of microcapsules BASF SE (DE) 2012-09-11 US disclosed
US-20110124590-A1 Oil-in-Water Emulsion Comprising Solvent, Water, Surfactant and Pesticide BASF SE (DE) 2011-05-26 US disclosed
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules BASF SE 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules MGAM, ACHE, BCHE CSNK1E 1043/4885CSNK1D 1071/4885DHODH 371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.