Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430781 | 0.87 | POLB (0.41) | POLBPLA2G10KMT2ASMN1; SMN2CSNK1E | |
| SCHEMBL27708027 | 0.85 | SCN9A (0.41) | POLBLMNACSNK1ENTRK1 | |
| SCHEMBL22534182 | 0.85 | POLB (0.40) | POLBPLA2G10CCNA2CDK2PLK1 | |
| SCHEMBL27719735 | 0.84 | POLB (0.39) | POLBPLA2G10CCNA2CDK2PLK1 | |
| SCHEMBL28930106 | 0.83 | GRM2 (0.39) | POLBGRM2MEN1KMT2APABPC1 | |
| SCHEMBL28248772 | 0.82 | POLB (0.51) | POLBPLA2G10CSF1RFGFR1FLT1 | |
| SCHEMBL3232399 | 0.82 | POLB (0.40) | POLBPLA2G10CSF1RFGFR1FLT1 | |
| SCHEMBL3865439 | 0.80 | POLB (0.39) | POLBPLA2G10CSF1RFGFR1FLT1 | |
| SCHEMBL18691185 | 0.80 | POLB (0.40) | POLBPLA2G10CSF1RFGFR1FLT1 | |
| SCHEMBL28963624 | 0.77 | POLB (0.38) | POLBPLA2G10GRM2KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113788790-A | Aromatic heterocyclic amide derivative and application thereof | 华东理工大学 | 2021-12-14 | — | — | CN | disclosed |