Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672577 | 0.92 | STAT3 (0.38) | STAT3STAT1 | |
| SCHEMBL28667173 | 0.81 | TOP1 (0.41) | STAT3STAT1 | |
| SCHEMBL28684342 | 0.81 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL28687619 | 0.79 | STAT3 (0.35) | STAT3STAT1 | |
| SCHEMBL27686681 | 0.78 | HDAC6 (0.40) | STAT3STAT1HDAC6SCDNPBWR1 | |
| SCHEMBL5062037 | 0.77 | STAT3 (0.53) | STAT3STAT1 | |
| SCHEMBL28839682 | 0.75 | STAT3 (0.34) | STAT3STAT1 | |
| SCHEMBL30505531 | 0.75 | STAT3 (0.38) | STAT3STAT1 | |
| SCHEMBL28113306 | 0.75 | STAT3 (0.38) | STAT3STAT1 | |
| SCHEMBL79329 | 0.75 | STAT3 (0.50) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831351-B | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | disclosed |