SCHEMBL5062037

SCHEMBL5062037

Brc1c2nc(cc3ccc([nH]3)c(Br)c3nc(cc4ccc1[nH]4)C=C3)C=C2

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.53
▸ STAT1 P42224 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8831500 0.97 STAT3 (0.50) STAT3STAT1
SCHEMBL79329 0.97 STAT3 (0.50) STAT3STAT1
SCHEMBL224519 0.95 STAT3 (0.48) STAT3STAT1
Phosphoric Acid SCHEMBL30944426 0.91 STAT3 (0.46) STAT3STAT1
SCHEMBL4168760 0.88 STAT3 (0.44) STAT3STAT1
SCHEMBL5134031 0.84 STAT3 (0.74) STAT3STAT1
SCHEMBL2940532 0.84 STAT3 (0.74) STAT3STAT1
SCHEMBL30767176 0.84 STAT3 (0.74) STAT3STAT1
SCHEMBL5011931 0.84 STAT3 (0.74) STAT3STAT1
SCHEMBL5134266 0.83 STAT3 (0.72) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113831351-B Novel tetrapyrrole derivatives and application thereof 上海先辉医药科技有限公司 2024-05-03 — — CN claimed
CN-113402536-B Porphyrin bridged double BODIPY derivative and preparation method thereof 南京林业大学 2022-04-19 — — CN claimed
CN-113831351-B Novel tetrapyrrole derivatives and application thereof 上海先辉医药科技有限公司 2024-05-03 — — CN disclosed
US-7417142-B2 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) 2008-08-26 — — US disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 — — US disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 — — US disclosed
US-5663328-A Haloporphyrins and their preparation and use as catalysts SUN COMPANY, INC. (R&M) (US) 1997-09-02 — — US disclosed
EP-0704447-A1 Reactions catalyzed by haloporphyrins SUN COMPANY, INC. (R&M) (US) 1996-04-03 — — EP disclosed
EP-0700915-A1 Haloporphyrins and their preparation SUN COMPANY, INC. (R&M) (US) 1996-03-13 — — EP disclosed
US-5489716-A Reactions catalyzed by haloporphyrins SUN COMPANY, INC. (R&M) (US) 1996-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG STAT3 3817/4885STAT1 4312/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS STAT3 2986/4885STAT1 3579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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