SCHEMBL79329

SCHEMBL79329

Brc1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.50
▸ STAT1 P42224 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5062037 0.97 STAT3 (0.53) STAT3STAT1
SCHEMBL224519 0.95 STAT3 (0.48) STAT3STAT1
SCHEMBL8831500 0.93 STAT3 (0.50) STAT3STAT1
SCHEMBL4168760 0.88 STAT3 (0.44) STAT3STAT1
Phosphoric Acid SCHEMBL30944426 0.88 STAT3 (0.46) STAT3STAT1
SCHEMBL722603 0.83 STAT3 (0.50) STAT3STAT1
SCHEMBL51570 0.82 STAT3 (0.59) STAT3STAT1
SCHEMBL6479855 0.82 STAT3 (0.49) STAT3STAT1
SCHEMBL38329 0.82 STAT3 (0.49) STAT3STAT1
SCHEMBL9866324 0.82 STAT3 (0.49) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024583-A Preparation and application of compound containing biporphyrin 中南大学 2021-06-25 — — CN claimed
CN-118852182-A Porphyrin-like chrysin conjugate and synthetic method and application thereof 中南大学 2024-10-29 — — CN disclosed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 — — CN disclosed
CN-116813626-A Chiral porphyrin ligand and preparation method thereof, chiral metalloporphyrin complex and application thereof 南方科技大学 2023-09-29 — — CN disclosed
CN-114907571-B Preparation and application of Eu metal-organic framework material based on difunctional pyridine carboxylic acid porphyrin ligand 北京工业大学 2023-09-12 — — CN disclosed
CN-113698579-B Porphyrin conjugated microporous polymer and its synthesis method and application 西北民族大学 2023-09-01 — — CN disclosed
CN-114854033-B Preparation and application of Eu metal-organic framework material based on non-planar porphyrin ligand 北京工业大学 2023-09-01 — — CN disclosed
CN-114621453-B Preparation and application of zirconium metal organic framework material of difunctional pyridine carboxylic acid porphyrin ligand 北京工业大学 2023-06-30 — — CN disclosed
US-11495368-B2 Hydrophobic, conductive organic materials for metallic surfaces INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2022-11-08 — — US disclosed
CN-114907571-A Preparation and application of Eu metal-organic framework material based on bifunctional pyridine carboxylic acid porphyrin ligand 北京工业大学 2022-08-16 — — CN disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 — — US disclosed
WO-2004109768-A2 METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES NORTH CAROLINA STATE UNIVERSITY (US) 2004-12-16 — — WO disclosed
US-20040254383-A1 Reacting a dipyrromethane with an oxidant and a metal salt to produce the bis(dipyrrinato)metal complex; for making molecular memory devices, solar cells and light harvesting arrays UNITED STATE DEPARTMENT OF ENERGY 2004-12-16 — — US disclosed
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2003-12-25 — — US disclosed
US-6603070-B2 Convergent method for the synthesis of light harvesting rods. The rods are oligomers of the formula A1(Ab+1)b, wherein b is at least 1, A1 through Ab+1 are covalently coupled rod segments, and each rod segment A1 through A1+b comprises a NORTH CAROLINA STATE UNIVERSITY 2003-08-05 — — US disclosed
US-20030111108-A1 Convergent synthesis of multiporphyrin light-harvesting rods UNITED STATES DEPARTMENT OF ENERGY 2003-06-19 — — US disclosed
US-5663328-A Haloporphyrins and their preparation and use as catalysts SUN COMPANY, INC. (R&M) (US) 1997-09-02 — — US disclosed
EP-0704447-A1 Reactions catalyzed by haloporphyrins SUN COMPANY, INC. (R&M) (US) 1996-04-03 — — EP disclosed
EP-0700915-A1 Haloporphyrins and their preparation SUN COMPANY, INC. (R&M) (US) 1996-03-13 — — EP disclosed
US-5489716-A Reactions catalyzed by haloporphyrins SUN COMPANY, INC. (R&M) (US) 1996-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254383-A1 Reacting a dipyrromethane with an oxidant and a metal salt to produce the bis(dipyrrinato)metal complex; for making molecular memory devices, solar cells and light harvesting arrays PPOX, NCS1, CRY1 STAT3 750/4885STAT1 2028/4885
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same PPOX, HMBS, UROD STAT3 4156/4885STAT1 3973/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS STAT3 2986/4885STAT1 3579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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