Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931499 | 0.92 | BCHE (0.50) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28962431 | 0.81 | MEN1 (0.76) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28931485 | 0.76 | MEN1 (0.71) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL19771114 | 0.75 | POLB (0.74) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28931495 | 0.74 | MEN1 (0.69) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL12854481 | 0.70 | RAB9A (0.45) | NPC1KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL31717641 | 0.68 | DYRK1A (0.69) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6227275 | 0.68 | MAPT (0.73) | NPC1POLBALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL10695859 | 0.67 | MAPT (0.75) | NPC1POLBALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL2752606 | 0.67 | ALDH1A1 (0.74) | NPC1KMT2AMEN1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417833-B | Synthesis method of 2-amido naphtho [1,2-d ] thiazole | 池州学院 | 2024-05-28 | — | — | CN | disclosed |
| CN-115417833-A | Synthesis method of 2-acylamino naphtho [1,2-d ] thiazole | 池州学院 | 2022-12-02 | — | — | CN | disclosed |