Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 6/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689284 | 0.92 | ENPP1 (0.56) | ENPP1KITPDGFRBMTNR1BPDE3B | |
| SCHEMBL29355270 | 0.86 | ENPP1 (0.60) | ENPP1PDGFRBPDE3BPDE3APDE10A | |
| SCHEMBL28931602 | 0.85 | ENPP1 (0.61) | ENPP1KITPDGFRBMTNR1BPDE3B | |
| SCHEMBL28684968 | 0.85 | GAA (0.45) | — | |
| SCHEMBL22407459 | 0.83 | ENPP1 (0.61) | ENPP1KITPDGFRBMTNR1BPDE3B | |
| Urea SCHEMBL22441453 | 0.82 | ENPP1 (0.60) | ENPP1KITPDGFRBPDE10AMAPK1 | |
| SCHEMBL28931416 | 0.79 | NCF1 (0.53) | ENPP1CYP2D6 | |
| SCHEMBL31457627 | 0.77 | ENPP1 (0.72) | ENPP1KITPDGFRBMTNR1BMAPK1 | |
| SCHEMBL28689286 | 0.77 | ENPP1 (0.72) | ENPP1KITPDGFRBMTNR1BMAPK1 | |
| SCHEMBL24392456 | 0.76 | KIT (0.55) | ENPP1KITPDGFRBMTNR1BPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924092-A | Quinoline and quinazoline compounds and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2022-01-11 | — | — | CN | disclosed |