Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | USP28 | Q96RU2 | 5/20 | 0.37 |
| ▸ | USP25 | Q9UHP3 | 5/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673972 | 0.86 | LMNA (0.46) | LMNASMN1; SMN2IDO1HTTMEN1 | |
| SCHEMBL19211018 | 0.82 | LMNA (0.41) | LMNASMN1; SMN2IDO1HTTMEN1 | |
| SCHEMBL19212145 | 0.82 | GRM5 (0.45) | LMNASMN1; SMN2IDO1HTTMEN1 | |
| SCHEMBL19212126 | 0.81 | LMNA (0.40) | LMNASMN1; SMN2IDO1HTTMEN1 | |
| SCHEMBL19212326 | 0.81 | USP25 (0.42) | LMNASMN1; SMN2IDO1HTTMEN1 | |
| SCHEMBL19212324 | 0.81 | USP25 (0.40) | LMNASMN1; SMN2IDO1HTTMEN1 | |
| SCHEMBL28681180 | 0.81 | NQO2 (0.39) | IDO1USP28USP25 | |
| SCHEMBL21457808 | 0.77 | ABCB1 (0.42) | IDO1MEN1KMT2AUSP28USP25 | |
| SCHEMBL29576850 | 0.77 | ABCB1 (0.42) | IDO1MEN1KMT2AUSP28USP25 | |
| SCHEMBL29707321 | 0.77 | ABCB1 (0.39) | LMNASMN1; SMN2IDO1KCNA5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |