SCHEMBL28931963

SCHEMBL28931963

Fc1cc(Cl)ccc1-c1cccc(Br)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
MEN1 O00255 2/20 0.43
HTT P42858 2/20 0.43
KMT2A Q03164 2/20 0.43
HPGD P15428 1/20 0.43
GCGR P47871 1/20 0.43
MAPK14 Q16539 1/20 0.43
CNR1 P21554 1/20 0.43
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRA5 P31644 1/20 0.42
GABRA3 P34903 1/20 0.42
GABRA2 P47869 1/20 0.42
GABRB2 P47870 1/20 0.42
GABRA4 P48169 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30404433 1.00 LMNA (0.43) LMNAMAPTMEN1HTTKMT2A
SCHEMBL30753844 0.81 CNR1 (0.44) LMNAMEN1KMT2AHPGDGCGR
SCHEMBL20898215 0.81 CNR1 (0.51) MEN1KMT2ACNR1GABRPGABRD
SCHEMBL20687344 0.81 MEN1 (0.44) LMNAMAPTMEN1HTTKMT2A
SCHEMBL8965191 0.81 CNR1 (0.44) LMNAMEN1KMT2AHPGDGCGR
SCHEMBL31067089 0.81 CNR1 (0.51) MEN1KMT2ACNR1GABRPGABRD
SCHEMBL16143069 0.81 AHR (0.52) LMNAMAPTMEN1HTTKMT2A
SCHEMBL23658448 0.80 MAPT (0.54) LMNAMAPTMEN1HTTKMT2A
SCHEMBL7821378 0.79 GRM2 (0.50) LMNAMAPTMEN1KMT2AHPGD
SCHEMBL30523575 0.79 RXFP1 (0.47) LMNAMAPTMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113950474-A Heterocyclic compound and organic light-emitting device including same LT素材株式会社 2022-01-18 CN disclosed