Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753844 | 1.00 | CNR1 (0.44) | CNR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10269901 | 0.85 | ALOX5AP (0.45) | CNR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL14926547 | 0.84 | CNR1 (0.49) | CNR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL15495645 | 0.82 | CNR1 (0.48) | CNR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30404433 | 0.81 | LMNA (0.43) | CNR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28931963 | 0.81 | LMNA (0.43) | CNR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27655365 | 0.80 | SMN1; SMN2 (0.54) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL20546438 | 0.78 | TTR (0.41) | CNR1KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL28513713 | 0.78 | GABRP (0.42) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL28663709 | 0.78 | GABRP (0.42) | GABRG2GABRB3GABRA5GABRA3GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |