Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | MMP15 | P51511 | 1/20 | 0.42 |
| ▸ | MMP16 | P51512 | 1/20 | 0.42 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400497 | 0.87 | MAPT (0.59) | HPGDSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL29187603 | 0.83 | HPGD (0.56) | HPGDSMN1; SMN2MAPTALDH1A1PAM | |
| SCHEMBL7732264 | 0.81 | MAPT (0.70) | HPGDSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL28933333 | 0.80 | NPC1 (0.39) | HPGDSMN1; SMN2MAPTALDH1A1PAM | |
| SCHEMBL10411946 | 0.78 | ACACB (0.49) | HPGDSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL28632566 | 0.78 | APP (0.61) | HPGDSMN1; SMN2MAPTALDH1A1PAM | |
| SCHEMBL21505679 | 0.78 | HPGD (0.45) | HPGDSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL24808421 | 0.76 | VCP (0.74) | HPGDSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL15960259 | 0.76 | RARB (0.55) | HPGDSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL15960257 | 0.75 | RARB (0.63) | HPGDSMN1; SMN2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583902-A | Preparation method of alkynyl thioether compound | 江苏医药职业学院 | 2023-01-10 | — | — | CN | disclosed |