Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467462 | 0.89 | ALDH1A1 (0.54) | CMA1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL10653121 | 0.84 | CMA1 (0.50) | CMA1PDE3BPDE3AGSK3BESR1 | |
| SCHEMBL10619933 | 0.84 | CMA1 (0.50) | CMA1PDE3BPDE3AMAPTESR1 | |
| SCHEMBL2317568 | 0.80 | CMA1 (0.56) | CMA1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL10650863 | 0.79 | CMA1 (0.54) | CMA1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL1324743 | 0.78 | PDE3B (0.44) | CMA1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL9684031 | 0.76 | PDE3B (0.42) | CMA1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL14565007 | 0.75 | PARP1 (0.50) | CMA1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL4195687 | 0.74 | CMA1 (0.45) | CMA1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL10619844 | 0.74 | CMA1 (0.42) | CMA1ALDH1A1PDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109419802-B | Compounds having dopamine D3 receptor modulating activity and uses thereof | 中国人民解放军军事医学科学院毒物药物研究所（CN） | 2023-01-13 | — | — | CN | disclosed |