Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324743 | 0.91 | PDE3B (0.44) | PDE3BPDE3AESR1PGRCMA1 | |
| SCHEMBL9483701 | 0.87 | PDE3B (0.43) | PDE3BPDE3AESR1PGRCMA1 | |
| SCHEMBL5467462 | 0.86 | ALDH1A1 (0.54) | PDE3BPDE3AESR1PGRCMA1 | |
| SCHEMBL8785075 | 0.85 | PDE3B (0.42) | PDE3BPDE3AESR1PGRCMA1 | |
| SCHEMBL9484623 | 0.85 | SIGMAR1 (0.50) | PDE3BPDE3AESR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL7252525 | 0.84 | HSD17B3 (0.50) | PDE3BPDE3AESR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL9483493 | 0.82 | CYP1A2 (0.51) | PDE3BPDE3AESR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9484788 | 0.82 | ESR1 (0.48) | PDE3BPDE3AESR1PGRMAPT | |
| SCHEMBL4200234 | 0.80 | PDE3B (0.45) | PDE3BPDE3AESR1PGRCMA1 | |
| SCHEMBL9483042 | 0.80 | ESR1 (0.52) | PDE3BPDE3AESR1PGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |