Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28709110 | 0.89 | ANPEP (0.46) | ATMNPSR1CNR2KCNN4KMT2A | |
| SCHEMBL28710172 | 0.89 | ANPEP (0.46) | ATMNPSR1CNR2KCNN4KMT2A | |
| SCHEMBL7036247 | 0.82 | NPSR1 (0.69) | ATMNPSR1CNR2KMT2AALDH1A1 | |
| SCHEMBL28934073 | 0.77 | HDAC3 (0.51) | ATMNPSR1CNR2KMT2AALDH1A1 | |
| SCHEMBL28934074 | 0.77 | HDAC3 (0.51) | ATMNPSR1CNR2KMT2AALDH1A1 | |
| SCHEMBL11697241 | 0.77 | ATM (0.56) | ATMNPSR1CNR2KMT2AALDH1A1 | |
| SCHEMBL11646318 | 0.76 | ATM (0.55) | ATMNPSR1CNR2KMT2AALDH1A1 | |
| SCHEMBL2485730 | 0.75 | ALDH1A1 (0.57) | ATMNPSR1CNR2KMT2AALDH1A1 | |
| SCHEMBL9298424 | 0.75 | ALDH1A1 (0.57) | ATMNPSR1CNR2KMT2AALDH1A1 | |
| SCHEMBL844431 | 0.74 | ATM (0.56) | ATMNPSR1CNR2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181116-A | D-amino acid derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2022-03-15 | — | — | CN | disclosed |