SCHEMBL28934052

SCHEMBL28934052

C[C@H](NN1CCC[C@H]1C(=O)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACE P12821 9/20 0.43
REN P00797 4/20 0.43
LMNA P02545 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
F2 P00734 1/20 0.43
LTA4H P09960 1/20 0.43
MAPT P10636 1/20 0.43
PEPD P12955 1/20 0.43
ALOX15 P16050 1/20 0.43
PTGS1 P23219 1/20 0.43
HTR2A P28223 1/20 0.43
PTGS2 P35354 1/20 0.43
HRH1 P35367 1/20 0.43
THPO P40225 1/20 0.43
PMP22 Q01453 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
RAB9A P51151 1/20 0.42
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31146386 0.83 ACE (0.41) ACERENLMNAHSD17B10KDM4E
SCHEMBL29937547 0.82 ACE (0.40) ACERENLMNAHSD17B10KDM4E
SCHEMBL29801994 0.80 RAB9A (0.43) ACERENLMNAHSD17B10KDM4E
SCHEMBL31515793 0.77 ACE (0.38) ACERENLMNAHSD17B10KDM4E
SCHEMBL6545198 0.76 KDM4E (0.40) LMNAHSD17B10KDM4E
SCHEMBL4737549 0.76 ACE (0.41) ACERENLMNAHSD17B10KDM4E
SCHEMBL28789104 0.76 ACE (0.41) ACERENLMNAHSD17B10KDM4E
SCHEMBL31245567 0.76 ACE (0.47) ACERENLMNAHSD17B10KDM4E
SCHEMBL22436906 0.76 ACE (0.47) ACERENLMNAHSD17B10KDM4E
SCHEMBL30618045 0.76 ACE (0.47) ACERENLMNAHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315510-B1 MODIFIED CHEMOKINE PEPTIDE RISE BIOPHARMACEUTICALS INC BEIJING (CN) 2025-02-19 EP claimed
EP-4351728-A2 METHODS OF USE OF ANTI-SORTILIN ANTIBODIES Alector LLC (US) 2024-04-17 EP disclosed
WO-2023220501-A1 ACTIVATABLE THERAPEUTIC PEPTIDES AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-11-16 WO disclosed
EP-4208188-A1 ANALOGS OF HUMAN FIBROBLAST GROWTH FACTORS Energesis Pharmaceuticals Inc. (US) 2023-07-12 EP disclosed
WO-2023081898-A1 SOLUBLE CD33 AS A BIOMARKER FOR ANTI-CD33 EFFICACY ALECTOR LLC (US) 2023-05-11 WO disclosed
WO-2022261648-A2 METHODS OF USE OF ANTI-SORTILIN ANTIBODIES ALECTOR LLC (US) 2022-12-15 WO disclosed
CN-108064248-B Human anti-dipeptide repeat (DPR) antibodies 生物控股有限公司 2022-03-15 CN disclosed