Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28934052 | 0.76 | ACE (0.43) | KDM4EHSD17B10LMNA | |
| SCHEMBL4907901 | 0.73 | MGLL (0.31) | — | |
| SCHEMBL385712 | 0.71 | L3MBTL1 (0.36) | KDM4EALDH1A1GAAHTT | |
| SCHEMBL385711 | 0.71 | L3MBTL1 (0.36) | KDM4EALDH1A1GAAHTT | |
| SCHEMBL383047 | 0.70 | L3MBTL1 (0.39) | KDM4EALDH1A1GAALMNAHTT | |
| SCHEMBL383046 | 0.70 | L3MBTL1 (0.39) | KDM4EALDH1A1GAALMNAHTT | |
| SCHEMBL23933724 | 0.69 | ALDH1A1 (0.43) | KDM4EHRH3ALDH1A1HSD17B10GAA | |
| SCHEMBL6336369 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL29053381 | 0.69 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL8723669 | 0.67 | HTT (0.39) | KDM4EALDH1A1GAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931792-B1 | Depsipeptides containing non-natural amino acids | NISSHIN SEIFUN GROUP INC (JP) | 2004-01-07 | — | — | EP | claimed |
| US-6316406-B1 | POLYPEPTIDES | NISSHIN SEIFUN GROUP INC. (JP) | 2001-11-13 | — | — | US | claimed |
| US-6252041-B1 | Depsipeptides containing non-natural amino acids | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2001-06-26 | — | — | US | claimed |
| US-6211145-B1 | PRODUCTION OF APOLYPOPROTEIN E | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2001-04-03 | — | — | US | claimed |
| EP-0989136-A1 | PEPTIDES HAVING CYCLIC STRUCTURES AND EXERTING P53 PROTEIN ACTIVTY-RESTORING EFFECT ON P53 PROTEIN MUTANTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-03-29 | — | — | EP | claimed |
| US-6001815-A | ALZHEIMER'S DISEASE; ANTILIPEMIC AGENT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-12-14 | — | — | US | claimed |
| EP-0934952-A2 | Peptides containing an N-substituted glycine residue | Nisshin Flour Milling Co., Ltd. (JP) | 1999-08-11 | — | — | EP | claimed |
| EP-0931792-A1 | Depsipeptides containing non-natural amino acids | Nisshin Flour Milling Co., Ltd. (JP) | 1999-07-28 | — | — | EP | claimed |
| EP-0927723-A1 | Bicyclic depsipeptides promoting the production of apolipoprotein E | Nisshin Flour Milling Co., Ltd. (JP) | 1999-07-07 | — | — | EP | claimed |
| EP-0931792-B1 | Depsipeptides containing non-natural amino acids | NISSHIN SEIFUN GROUP INC (JP) | 2004-01-07 | — | — | EP | disclosed |
| US-6316406-B1 | POLYPEPTIDES | NISSHIN SEIFUN GROUP INC. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6211145-B1 | PRODUCTION OF APOLYPOPROTEIN E | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0989136-A1 | PEPTIDES HAVING CYCLIC STRUCTURES AND EXERTING P53 PROTEIN ACTIVTY-RESTORING EFFECT ON P53 PROTEIN MUTANTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |
| US-6001815-A | ALZHEIMER'S DISEASE; ANTILIPEMIC AGENT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| EP-0934952-A2 | Peptides containing an N-substituted glycine residue | Nisshin Flour Milling Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
| EP-0931792-A1 | Depsipeptides containing non-natural amino acids | Nisshin Flour Milling Co., Ltd. (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0927723-A1 | Bicyclic depsipeptides promoting the production of apolipoprotein E | Nisshin Flour Milling Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |