Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.80 |
| ▸ | IL1B | P01584 | 12/20 | 0.62 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108858 | 1.00 | NLRP3 (0.80) | NLRP3IL1BKAT2B | |
| SCHEMBL28934554 | 1.00 | NLRP3 (0.80) | NLRP3IL1BKAT2B | |
| SCHEMBL28934288 | 0.96 | NLRP3 (0.80) | NLRP3IL1B | |
| SCHEMBL28934284 | 0.96 | NLRP3 (0.80) | NLRP3IL1B | |
| SCHEMBL30101031 | 0.96 | NLRP3 (0.80) | NLRP3IL1B | |
| SCHEMBL24840759 | 0.93 | NLRP3 (0.79) | NLRP3IL1BKAT2B | |
| SCHEMBL30040144 | 0.93 | NLRP3 (0.79) | NLRP3IL1BKAT2B | |
| SCHEMBL24840289 | 0.93 | NLRP3 (0.79) | NLRP3IL1BKAT2B | |
| SCHEMBL28965247 | 0.91 | IL1B (0.77) | NLRP3IL1B | |
| SCHEMBL28934765 | 0.91 | NLRP3 (0.67) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |