SCHEMBL28935583

SCHEMBL28935583

N#Cc1ccc(C2CCO2)cc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CYP19A1 P11511 6/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP2A6 P11509 1/20 0.38
CA12 O43570 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CYP11B1 P15538 3/20 0.36
CYP11B2 P19099 3/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13014690 0.90 KCNH2 (0.44) MAOAMAOBCYP19A1CYP11B1CYP11B2
SCHEMBL9906430 0.89 KCNH2 (0.46) MAOAMAOBCYP19A1CYP11B1CYP11B2
SCHEMBL21677893 0.84 CYP19A1 (0.35) CYP19A1
SCHEMBL21678034 0.84 CYP19A1 (0.35) CYP19A1
SCHEMBL1225841 0.83 TSHR (0.50) MAOAMAOBCYP19A1ALDH1A1CYP2A6
SCHEMBL1225840 0.83 TSHR (0.50) MAOAMAOBCYP19A1ALDH1A1CYP2A6
SCHEMBL1226208 0.83 TSHR (0.50) MAOAMAOBCYP19A1ALDH1A1CYP2A6
SCHEMBL7879783 0.80 DRD2 (0.50) KCNH2
SCHEMBL136333 0.80 DRD2 (0.50) KCNH2
Hydrochloric Acid SCHEMBL966629 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115612435-A High-temperature-resistant polyurethane adhesive for sealing and preparation method thereof 唯万科技有限公司 2023-01-17 CN disclosed