Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21677893 | 1.00 | CYP19A1 (0.35) | CYP19A1KDM1ABACE1LRRK2CYP2D6 | |
| SCHEMBL28935583 | 0.84 | MAOA (0.39) | CYP19A1 | |
| SCHEMBL20719816 | 0.78 | SLC6A2 (0.40) | KDM1A | |
| SCHEMBL21677966 | 0.78 | TSHR (0.48) | KDM1ACYP2D6 | |
| SCHEMBL13014690 | 0.76 | KCNH2 (0.44) | CYP19A1 | |
| SCHEMBL27478102 | 0.75 | KIF11 (0.34) | CYP19A1BACE1 | |
| SCHEMBL9906430 | 0.75 | KCNH2 (0.46) | CYP19A1 | |
| SCHEMBL1226208 | 0.73 | TSHR (0.50) | CYP19A1KDM1A | |
| SCHEMBL1225841 | 0.73 | TSHR (0.50) | CYP19A1KDM1A | |
| SCHEMBL1225840 | 0.73 | TSHR (0.50) | CYP19A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275998-A1 | CATALYSTS, METHODS OF MAKING, AND METHODS OF HYDROFLUORINATION | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2021-09-09 | — | — | US | disclosed |
| WO-2020023354-A1 | CATALYSTS, METHODS OF MAKING, AND METHODS OF HYDROFLUORINATION | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275998-A1 | CATALYSTS, METHODS OF MAKING, AND METHODS OF HYDROFLUORINATION | FLI1, EWSR1, KRAS | CYP19A1 566/4885KDM1A 891/4885BACE1 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.