Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NNMT | P40261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091456 | 0.81 | POLB (0.42) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL323351 | 0.79 | POLB (0.55) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL586103 | 0.79 | NNMT (0.53) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL12588525 | 0.79 | NNMT (0.44) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL19671122 | 0.77 | POLB (0.40) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL1851105 | 0.77 | NNMT (0.43) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL30619421 | 0.77 | POLB (0.40) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL15467080 | 0.77 | POLB (0.40) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL30427669 | 0.77 | NNMT (0.43) | POLBTDP1NNMTCYP1A2KMT2A | |
| SCHEMBL13213488 | 0.77 | POLB (0.40) | POLBTDP1NNMTCYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611925-A | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-01-17 | — | — | CN | disclosed |