Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 4/20 | 0.39 |
| ▸ | NNMT | P40261 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15542562 | 0.78 | POLB (0.36) | POLBTDP1NQO2NNMTKMT2A | |
| SCHEMBL15908313 | 0.78 | MAPT (0.40) | TDP1NPC1RAB9AL3MBTL1 | |
| SCHEMBL28935930 | 0.77 | POLB (0.42) | POLBTDP1NNMTKMT2AERN1 | |
| SCHEMBL2969903 | 0.77 | CYP1A2 (0.41) | POLBTDP1NQO2NNMTKMT2A | |
| SCHEMBL30207735 | 0.77 | CYP1A2 (0.41) | POLBTDP1NQO2NNMTKMT2A | |
| SCHEMBL1460108 | 0.76 | POLB (0.50) | POLBTDP1NQO2NNMTKMT2A | |
| SCHEMBL29850137 | 0.76 | POLB (0.50) | POLBTDP1NQO2NNMTKMT2A | |
| SCHEMBL1461146 | 0.76 | NNMT (0.48) | POLBTDP1NQO2NNMTKMT2A | |
| SCHEMBL12588525 | 0.76 | NNMT (0.44) | POLBTDP1NNMTKMT2AERN1 | |
| SCHEMBL1758829 | 0.75 | POLB (0.38) | POLBTDP1NQO2NNMTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132542-A1 | MACROCYCLIC OREXIN AGONISTS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-26 | — | — | WO | disclosed |
| EP-3251674-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BioCryst Pharmaceuticals, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |