Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195201 | 0.87 | MAPT (0.60) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL6196541 | 0.87 | MAPT (0.60) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL6197167 | 0.87 | MAPT (0.60) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL28936152 | 0.82 | MAPT (0.51) | ALDH1A1LMNAMAPTGAAHTT | |
| SCHEMBL4245020 | 0.77 | AR (0.60) | ALDH1A1LMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL3620476 | 0.77 | AR (0.60) | ALDH1A1LMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL4826536 | 0.77 | ALDH1A1 (0.73) | ALDH1A1LMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL31702110 | 0.77 | ALDH1A1 (0.73) | ALDH1A1LMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL28773806 | 0.75 | MAPT (0.58) | ALDH1A1LMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL29606963 | 0.75 | MAPT (0.58) | ALDH1A1LMNAMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020957-B | Heterocyclic compounds as MNK inhibitors | 南京天印健华医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |