SCHEMBL28936152 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	5/20	0.51

▸	ALDH1A1	P00352	2/20	0.51

▸	LMNA	P02545	2/20	0.51

▸	POLB	P06746	1/20	0.40

▸	HTT	P42858	2/20	0.37

▸	KMT2A	Q03164	2/20	0.37

▸	HTR7	P34969	1/20	0.36

▸	GAA	P10253	1/20	0.35

▸	HTR1A	P08908	2/20	0.35

▸	HTR2C	P28335	1/20	0.34

▸	HSD11B1	P28845	1/20	0.34

▸	BRPF1	P55201	2/20	0.34

▸	BRD4	O60885	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6195201	0.84	MAPT (0.60)	MAPTALDH1A1LMNAHTTKMT2A
SCHEMBL6196541	0.84	MAPT (0.60)	MAPTALDH1A1LMNAHTTKMT2A
SCHEMBL6197167	0.84	MAPT (0.60)	MAPTALDH1A1LMNAHTTKMT2A
SCHEMBL28936147	0.82	ALDH1A1 (0.53)	MAPTALDH1A1LMNAHTTKMT2A
SCHEMBL28936369	0.78	HDAC1 (0.42)	MAPTALDH1A1LMNAKMT2AGAA
SCHEMBL5235239	0.76	CTSB (0.53)	MAPTALDH1A1LMNAPOLBHTT
SCHEMBL4245020	0.75	AR (0.60)	MAPTALDH1A1LMNAHTTGAA
SCHEMBL3620476	0.75	AR (0.60)	MAPTALDH1A1LMNAHTTGAA
SCHEMBL6202631	0.75	MAPT (0.39)	MAPTALDH1A1LMNAPOLBHTT
SCHEMBL2895166	0.72	CYP1A2 (0.60)	MAPTALDH1A1LMNAPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-109020957-B	Heterocyclic compounds as MNK inhibitors	南京天印健华医药科技有限公司（CN）	2023-01-13	—	—	CN	disclosed