SCHEMBL28936744

SCHEMBL28936744

O=S(=O)(Sc1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.63
CA2 P00918 4/20 0.48
PLCG1 P19174 1/20 0.46
MMP2 P08253 4/20 0.43
CA12 O43570 4/20 0.43
CA9 Q16790 3/20 0.43
CA1 P00915 2/20 0.43
MMP1 P03956 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
F2 P00734 2/20 0.39
PRSS1 P07477 2/20 0.39
PRSS2 P07478 2/20 0.39
PRSS3 P35030 2/20 0.39
IDO1 P14902 1/20 0.39
CA14 Q9ULX7 2/20 0.38
AKR1B1 P15121 1/20 0.38
GAA P10253 1/20 0.37
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28229835 0.90 DNMT1 (0.81) DNMT1CA2PLCG1CA12CA9
SCHEMBL31411267 0.77 DNMT1 (0.63) DNMT1CA2CA12CA9CA1
SCHEMBL3917191 0.77 DNMT1 (1.00) DNMT1CA2MMP2CA12CA9
SCHEMBL7531692 0.77 DNMT1 (0.63) DNMT1CA2MMP2CA1MMP1
SCHEMBL3238479 0.77 DNMT1 (0.63) DNMT1CA2MMP2CA12CA9
SCHEMBL11293341 0.77 DNMT1 (0.63) DNMT1CA2MMP2CA12CA9
SCHEMBL16882624 0.74 CA2 (0.50) CA2PLCG1MMP2CA12CA9
SCHEMBL15076023 0.74 CA2 (0.50) DNMT1CA2PLCG1MMP2CA12
SCHEMBL10396837 0.73 CA2 (0.48) CA2PLCG1MMP2CA12CA9
SCHEMBL7537258 0.72 DNMT1 (0.62) DNMT1CA2MMP2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213298-B Method for preparing thiosulfonate compound by directly oxidizing thiophenol 南昌大学 2022-12-06 CN disclosed
CN-114213298-A Method for preparing thiosulfonate compound by directly oxidizing thiophenol 南昌大学 2022-03-22 CN disclosed