Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 1.00 |
| ▸ | G6PD | P11413 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 7/20 | 0.47 |
| ▸ | ACHE | P22303 | 7/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28229835 | 0.90 | DNMT1 (0.81) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL10330810 | 0.90 | DNMT1 (0.81) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL10330809 | 0.90 | DNMT1 (0.81) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL11290137 | 0.90 | DNMT1 (0.81) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL7115923 | 0.86 | DNMT1 (0.73) | DNMT1GAACA1CA2CA12 | |
| SCHEMBL23312332 | 0.79 | DNMT1 (0.63) | DNMT1G6PDCA1CA2CA7 | |
| SCHEMBL28711548 | 0.78 | DNMT1 (0.64) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL2038233 | 0.78 | DNMT1 (0.64) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL733650 | 0.78 | DNMT1 (0.64) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL7531692 | 0.77 | DNMT1 (0.63) | DNMT1GAACA1CA2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964529-A | Method for synthesizing E-alkenyl thioether compound | 江苏海洋大学 | 2024-05-03 | — | — | CN | disclosed |
| US-9657027-B2 | Processes for making hydrocodone, hydromorphone and their derivatives | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-05-23 | — | — | US | disclosed |
| US-9657028-B2 | Processes for making hydrocodone, hydromorphone and their derivatives | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-05-23 | — | — | US | disclosed |
| US-20160137656-A1 | PROCESSES FOR MAKING HYDROCODONE, HYDROMORPHONE AND THEIR DERIVATIVES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2016-05-19 | — | — | US | disclosed |
| US-20160137655-A1 | PROCESSES FOR MAKING HYDROCODONE, HYDROMORPHONE AND THEIR DERIVATIVES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2016-05-19 | — | — | US | disclosed |
| US-9273060-B2 | Processes for making hydrocodone, hydromorphone and their derivatives | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2016-03-01 | — | — | US | disclosed |
| US-20150252052-A1 | PROCESSES FOR MAKING HYDROCODONE, HYDROMORPHONE AND THEIR DERIVATIVES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2015-09-10 | — | — | US | disclosed |
| US-20090221711-A1 | TRIFLUOROMETHYL-CONTAINING PHENYLSULFONAMIDE BETA AMYLOID INHIBITORS | WYETH (US) | 2009-09-03 | — | — | US | disclosed |
| US-7550629-B2 | 4-chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]benzenesulfonamide; 4-cyano-N-(3,3,3-trifluoro-1-hydroxymethyl-2-trifluoromethyl-propyl)-benzenesulfonamide; Alzheimer's Disease, amyloid angiopathy, systemic amyloidosis, mild cognitive impairment and Down's syndrome | WYETH (US) | 2009-06-23 | — | — | US | disclosed |
| US-20090117346-A1 | PHOTOSENSITIVE MATERIAL FOR FORMING CONDUCTIVE FILM, CONDUCTIVE FILM, LIGHT TRANSMITTING ELECTROMAGNETIC WAVE SHIELDING FILM AND METHOD FOR MANUFACTURING THE SAME | FUJIFILM CORPORATION (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20070249722-A1 | Trifluoromethyl-containing phenylsulfonamide beta amyloid inhibitors | WYETH (US) | 2007-10-25 | — | — | US | disclosed |
| US-20070249723-A1 | Methods for preparing sulfonamide compounds | WYETH (US) | 2007-10-25 | — | — | US | disclosed |
| US-7220537-B2 | Silver halide emulsion silver halide photographic sensitive material and method of image formation | KONICA MINOLTA PHOTO IMAGING, INC. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7163784-B2 | Silver halide emulsion, and silver halide color photographic material using the same | KONICA MINOLTA PHOTO IMAGING, INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163784-B2 | Silver halide emulsion, and silver halide color photographic material using the same | KONICA MINOLTA PHOTO IMAGING, INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-6559170-B1 | Compounds are useful as fungicides in plants | DOW AGROSCIENCE LLC | 2003-05-06 | — | — | US | disclosed |
| EP-1237870-A1 | PYRIDINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO PRODUCE AND USE THE SAME | Dow AgroSciences LLC (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044196-A1 | PYRIDINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO PRODUCE AND USE THE SAME | DOW AGROSCIENCES, LLC (US) | 2001-06-21 | — | — | WO | disclosed |
| EP-0538898-A2 | Cytotoxic bicyclo (7.3.1)-tridec-4-ene-2,6-diyne compounds and process for the preparation thereof | Bristol-Myers Squibb Company (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0454146-A1 | Cytotoxic bicyclo[7.3.1] tridec-4-ene-2,6-diyne compounds and process for the preparation thereof | Bristol-Myers Squibb Company (US) | 1991-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221711-A1 | TRIFLUOROMETHYL-CONTAINING PHENYLSULFONAMIDE BETA AMYLOID INHIBITORS | APP, PSEN1, BACE1 | DNMT1 3734/4885G6PD 1814/4885GAA 849/4885 |
| US-20070249722-A1 | Trifluoromethyl-containing phenylsulfonamide beta amyloid inhibitors | APP, PSEN1, BACE1 | DNMT1 3734/4885G6PD 1814/4885GAA 849/4885 |
| US-20070249723-A1 | Methods for preparing sulfonamide compounds | PNISR, RRM1, MRPS27 | DNMT1 1502/4885G6PD 1495/4885GAA 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.