Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FGB | P02675 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855872 | 0.85 | GSTP1 (0.46) | ALDH1A1EGLN1HPGDHSD17B10POLB | |
| SCHEMBL29506066 | 0.85 | GSTP1 (0.46) | ALDH1A1EGLN1HPGDHSD17B10POLB | |
| SCHEMBL28615837 | 0.77 | NOTUM (0.48) | ALDH1A1SLC22A12KDM4ECDC25BPRNP | |
| SCHEMBL13401493 | 0.75 | SLC6A5 (0.47) | ALDH1A1KDM4EHPGDPOLBAPEX1 | |
| SCHEMBL28453832 | 0.73 | SLC22A12 (0.44) | ALDH1A1SLC22A12KDM4ECDC25BKMT2A | |
| SCHEMBL28408913 | 0.70 | ALDH1A1 (0.47) | ALDH1A1SLC22A12KDM4EHPGDHSD17B10 | |
| SCHEMBL1701301 | 0.70 | CA12 (0.33) | HSD17B10MAPK1L3MBTL1 | |
| SCHEMBL24980489 | 0.69 | APEX1 (0.42) | ALDH1A1POLBMEN1FGBKMT2A | |
| SCHEMBL1664968 | 0.68 | KDM4C (0.46) | ALDH1A1EGLN1KDM4EMEN1KMT2A | |
| SCHEMBL29507247 | 0.68 | KDM4C (0.46) | ALDH1A1EGLN1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341124-A | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2022-04-12 | — | — | CN | disclosed |