Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349922 | 0.79 | MEN1 (0.43) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL22529957 | 0.79 | MEN1 (0.43) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL22530094 | 0.79 | KDM4E (0.43) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL29351821 | 0.79 | KDM4E (0.43) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL26140408 | 0.75 | MEN1 (0.39) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL28704648 | 0.73 | KDM4E (0.41) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL22530943 | 0.72 | MAPK8 (0.38) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL22529924 | 0.72 | AURKA (0.38) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL29350344 | 0.72 | MAPK8 (0.38) | ABL1MAPK14AURKANTRK1LCK | |
| SCHEMBL29352030 | 0.72 | AURKA (0.38) | ABL1MAPK14AURKANTRK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007696-A | Compounds for treating oncovirus-induced cancer and methods of use thereof | 塞莱斯蒂亚生物技术股份公司 | 2022-02-01 | — | — | CN | disclosed |